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IDENTIFICATION OF THE RATE-DETERMINING STEP OF tRNA-GUANINE TRANSGLYCOSYLASE FROM E. coli

The modified RNA base queuine (7-(4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine) occurs in tRNA via a unique base exchange process catalyzed by tRNA-guanine transglycosylase (TGT). Previous studies have suggested the intermediacy of a covalent TGT-RNA complex. To exist on the react...

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Bibliografski detalji
Glavni autori: Garcia, George A., Chervin, Stephanie M., Kittendorf, Jeffrey D.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789984/
https://ncbi.nlm.nih.gov/pubmed/19874048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901501a
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