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Statistical Methods for Analysis of High-Throughput RNA Interference Screens

RNA interference (RNAi) has become a powerful technique for reverse genetics and drug discovery and, in both of these areas, large-scale high-throughput RNAi screens are commonly performed. The statistical techniques used to analyze these screens are frequently borrowed directly from small-molecule...

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Detalhes bibliográficos
Main Authors: Birmingham, Amanda, Selfors, Laura M., Forster, Thorsten, Wrobel, David, Kennedy, Caleb J., Shanks, Emma, Santoyo-Lopez, Javier, Dunican, Dara J., Long, Aideen, Kelleher, Dermot, Smith, Queta, Beijersbergen, Roderick L., Ghazal, Peter, Shamu, Caroline E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789971/
https://ncbi.nlm.nih.gov/pubmed/19644458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1351
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