Effects of muscarinic receptor stimulation on Ca(2+) transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells

We investigated the contribution of the intracellular calcium (Ca(i)(2+)) transient to acetylcholine (ACh)-mediated reduction of pacemaker frequency and cAMP content in rabbit sinoatrial nodal (SAN) cells. Action potentials (whole cell perforated patch clamp) and Ca(i)(2+) transients (Indo-1 fluores...

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Detalles Bibliográficos
Autores principales: van Borren, Marcel M. G. J., Verkerk, Arie O., Wilders, Ronald, Hajji, Najat, Zegers, Jan G., Bourier, Jan, Tan, Hanno L., Verheijck, Etienne E., Peters, Stephan L. M., Alewijnse, Astrid E., Ravesloot, Jan-Hindrik
Formato: Artigo
Lenguaje:Inglês
Publicado: D. Steinkopff-Verlag 2009
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Original Contribution
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789936/
https://ncbi.nlm.nih.gov/pubmed/19639379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-009-0048-9
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