Effects of muscarinic receptor stimulation on Ca(2+) transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells

We investigated the contribution of the intracellular calcium (Ca(i)(2+)) transient to acetylcholine (ACh)-mediated reduction of pacemaker frequency and cAMP content in rabbit sinoatrial nodal (SAN) cells. Action potentials (whole cell perforated patch clamp) and Ca(i)(2+) transients (Indo-1 fluores...

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Bibliografske podrobnosti
Main Authors: van Borren, Marcel M. G. J., Verkerk, Arie O., Wilders, Ronald, Hajji, Najat, Zegers, Jan G., Bourier, Jan, Tan, Hanno L., Verheijck, Etienne E., Peters, Stephan L. M., Alewijnse, Astrid E., Ravesloot, Jan-Hindrik
Format: Artigo
Jezik:Inglês
Izdano: D. Steinkopff-Verlag 2009
Teme:
Original Contribution
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789936/
https://ncbi.nlm.nih.gov/pubmed/19639379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-009-0048-9
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