Innate Immune Response to H3N2 and H1N1 Influenza Virus Infection in a Human Lung Organ Culture Model

We studied cytokine responses to influenza virus PR8 (H1N1) and Oklahoma/309/06 (OK/06, H3N2) in a novel human lung tissue model. Exposure of the model to influenza virus rapidly activated the mitogen activated protein kinase signaling (MAPK) pathways ERK, p38 and JNK. In addition, RNase protection...

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Huvudupphovsmän: Wu, Wenxin, Booth, J. Leland, Duggan, Elizabeth S., Wu, Shuhua, Patel, Krupa B., Coggeshall, K. Mark, Metcalf, Jordan P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789846/
https://ncbi.nlm.nih.gov/pubmed/19913271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.10.016
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