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Prion protein self-peptides modulate prion interactions and conversion
BACKGROUND: Molecular mechanisms underlying prion agent replication, converting host-encoded cellular prion protein (PrP(C)) into the scrapie associated isoform (PrP(Sc)), are poorly understood. Selective self-interaction between PrP molecules forms a basis underlying the observed differences of the...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789745/ https://ncbi.nlm.nih.gov/pubmed/19943977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-10-29 |
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