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The pathophysiology of paroxysmal nocturnal hemoglobinuria and treatment with eculizumab

Paroxysmal nocturnal hemoglobinuria is a rare disorder of hemopoietic stem cells. Affected individuals have a triad of clinical associations – intravascular hemolysis, an increased risk of thromboembolism, and bone marrow failure. Most of the symptoms experienced in this disease occur due to the abs...

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Détails bibliographiques
Auteurs principaux: Kelly, Richard, Richards, Stephen, Hillmen, Peter, Hill, Anita
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789686/
https://ncbi.nlm.nih.gov/pubmed/20011245
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