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Crystal Structures of the Histidine Acid Phosphatase from Francisella tularensis Provide Insight into Substrate Recognition

Histidine acid phosphatases catalyze the transfer of a phosphoryl group from phosphomonoesters to water at acidic pH using an active site histidine. The histidine acid phosphatase from the category A pathogen Francisella tularensis (FtHAP) has been implicated in intramacrophage survival and virulenc...

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Detalhes bibliográficos
Main Authors: Singh, Harkewal, Felts, Richard L., Schuermann, Jonathan P., Reilly, Thomas J., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789666/
https://ncbi.nlm.nih.gov/pubmed/19836403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.10.009
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