Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections

The septoclast is a specialized, cathepsin B-rich, perivascular cell type that accompanies invading capillaries on the metaphyseal side of the growth plate during endochondral bone growth. The putative role of septoclasts is to break down the terminal transverse septum of growth plate cartilage and...

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Autores principales: Gartland, Alison, Mason-Savas, April, Yang, Meiheng, MacKay, Carole A., Birnbaum, Mark J., Odgren, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2009
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789625/
https://ncbi.nlm.nih.gov/pubmed/19893052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090185
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