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BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures

Bone morphogenetic proteins (BMPs) play pivotal roles in bone and cartilage growth and repair. Through phenotypes of short ear mice, which have BMP-5 mutations, a role for BMP-5 in some specific aspects of skeletogenesis and cartilage growth is known. This report examines BMP-5 expression in the gro...

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Autores principales: Mailhot, Geneviève, Yang, Meiheng, Mason-Savas, April, MacKay, Carole A., Leav, Irwin, Odgren, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750834/
https://ncbi.nlm.nih.gov/pubmed/17541940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21164
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