Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

The enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyses the co-translational covalent attachment of the fatty acid myristate to the N-terminus of target proteins. NMT is known to be essential for viability in Trypanosoma brucei and Leishmania major. Here we describe phenotypic analys...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Price, Helen P., Güther, M. Lucia S., Ferguson, Michael A.J., Smith, Deborah F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier/North-Holland Biomedical Press 2010
Pynciau:
Short Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789243/
https://ncbi.nlm.nih.gov/pubmed/19782106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.09.006
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