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Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration

The plasminogen system plays a crucial role in the repair of a variety of tissues, including skeletal muscle. We hypothesized that urokinase-type plasminogen activator (uPA) promotes muscle regeneration by activating hepatocyte growth factor (HGF), which, in turn, stimulates proliferation of myoblas...

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Detalhes bibliográficos
Main Authors: Sisson, Thomas H., Nguyen, Mai-Huong, Yu, Bi, Novak, Margaret L., Simon, Richard H., Koh, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788978/
https://ncbi.nlm.nih.gov/pubmed/19812386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196212
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