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Architectural Nucleoporins Nup157/170 and Nup133 Are Structurally Related and Descend from a Second Ancestral Element

The nuclear pore complex (NPC) constitutes one of the largest protein assemblies in the eukaryotic cell and forms the exclusive gateway to the nucleus. The stable, ∼15–20-MDa scaffold ring of the NPC is built from two multiprotein complexes arranged around a central 8-fold axis. Here we present crys...

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Bibliografski detalji
Glavni autori: Whittle, James R. R., Schwartz, Thomas U.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788893/
https://ncbi.nlm.nih.gov/pubmed/19674973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023580
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