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Opposing Effects of KLF5 on the Transcription of MYC in Epithelial Proliferation in the Context of Transforming Growth Factor β
The proto-oncogene MYC plays a critical role in cell proliferation and tumorigenesis, and its down-regulation by transforming growth factor β (TGFβ) signaling is necessary for TGFβ to inhibit cell proliferation. KLF5, on the other hand, is a pro-proliferative basic transcription factor that reverses...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788876/ https://ncbi.nlm.nih.gov/pubmed/19684017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036160 |
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