Reduction of Lysyl Hydroxylase 3 Causes Deleterious Changes in the Deposition and Organization of Extracellular Matrix

Lysyl hydroxylase 3 (LH3) is a multifunctional enzyme possessing lysyl hydroxylase, collagen galactosyltransferase, and glucosyltransferase (GGT) activities. We report here an important role for LH3 in the organization of the extracellular matrix (ECM) and cytoskeleton. Deposition of ECM was affecte...

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Detaylı Bibliyografya
Asıl Yazarlar: Risteli, Maija, Ruotsalainen, Heli, Salo, Antti M., Sormunen, Raija, Sipilä, Laura, Baker, Naomi L., Lamandé, Shireen R., Vimpari-Kauppinen, Leena, Myllylä, Raili
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Glycobiology and Extracellular Matrices
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788872/
https://ncbi.nlm.nih.gov/pubmed/19696018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038190
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