Reduction of Lysyl Hydroxylase 3 Causes Deleterious Changes in the Deposition and Organization of Extracellular Matrix

Lysyl hydroxylase 3 (LH3) is a multifunctional enzyme possessing lysyl hydroxylase, collagen galactosyltransferase, and glucosyltransferase (GGT) activities. We report here an important role for LH3 in the organization of the extracellular matrix (ECM) and cytoskeleton. Deposition of ECM was affecte...

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Hlavní autoři: Risteli, Maija, Ruotsalainen, Heli, Salo, Antti M., Sormunen, Raija, Sipilä, Laura, Baker, Naomi L., Lamandé, Shireen R., Vimpari-Kauppinen, Leena, Myllylä, Raili
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788872/
https://ncbi.nlm.nih.gov/pubmed/19696018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038190
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