Reduction of Lysyl Hydroxylase 3 Causes Deleterious Changes in the Deposition and Organization of Extracellular Matrix

Lysyl hydroxylase 3 (LH3) is a multifunctional enzyme possessing lysyl hydroxylase, collagen galactosyltransferase, and glucosyltransferase (GGT) activities. We report here an important role for LH3 in the organization of the extracellular matrix (ECM) and cytoskeleton. Deposition of ECM was affecte...

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Detalhes bibliográficos
Main Authors: Risteli, Maija, Ruotsalainen, Heli, Salo, Antti M., Sormunen, Raija, Sipilä, Laura, Baker, Naomi L., Lamandé, Shireen R., Vimpari-Kauppinen, Leena, Myllylä, Raili
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788872/
https://ncbi.nlm.nih.gov/pubmed/19696018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038190
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