α-Defensins in Enteric Innate Immunity: FUNCTIONAL PANETH CELL α-DEFENSINS IN MOUSE COLONIC LUMEN

Paneth cells are a secretory epithelial lineage that release dense core granules rich in host defense peptides and proteins from the base of small intestinal crypts. Enteric α-defensins, termed cryptdins (Crps) in mice, are highly abundant in Paneth cell secretions and inherently resistant to proteo...

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Bibliographic Details
Main Authors: Mastroianni, Jennifer R., Ouellette, André J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788835/
https://ncbi.nlm.nih.gov/pubmed/19687006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050773
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