An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

Histone variant H2A.Z has a conserved role in genome stability, although it remains unclear how this is mediated. Here we demonstrate in fission yeast that the Swr1 ATPase inserts H2A.Z (Pht1) into chromatin and Kat5 acetyltransferase (Mst1) acetylates it. Deletion or unacetylatable mutation of Pht1...

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Détails bibliographiques
Auteurs principaux: Kim, Hyun-Soo, Vanoosthuyse, Vincent, Fillingham, Jeffrey, Roguev, Assen, Watt, Stephen, Kislinger, Thomas, Treyer, Alex, Carpenter, Laura Rocco, Bennett, Christopher S., Emili, Andrew, Greenblatt, Jack F., Hardwick, Kevin G., Krogan, Nevan J., Bähler, Jürg, Keogh, Michael-Christopher
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788674/
https://ncbi.nlm.nih.gov/pubmed/19915592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1688
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