An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

Histone variant H2A.Z has a conserved role in genome stability, although it remains unclear how this is mediated. Here we demonstrate in fission yeast that the Swr1 ATPase inserts H2A.Z (Pht1) into chromatin and Kat5 acetyltransferase (Mst1) acetylates it. Deletion or unacetylatable mutation of Pht1...

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Detalhes bibliográficos
Main Authors: Kim, Hyun-Soo, Vanoosthuyse, Vincent, Fillingham, Jeffrey, Roguev, Assen, Watt, Stephen, Kislinger, Thomas, Treyer, Alex, Carpenter, Laura Rocco, Bennett, Christopher S., Emili, Andrew, Greenblatt, Jack F., Hardwick, Kevin G., Krogan, Nevan J., Bähler, Jürg, Keogh, Michael-Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788674/
https://ncbi.nlm.nih.gov/pubmed/19915592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1688
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