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Alzheimer's disease: synaptic dysfunction and Aβ

Synapse loss is an early and invariant feature of Alzheimer's disease (AD) and there is a strong correlation between the extent of synapse loss and the severity of dementia. Accordingly, it has been proposed that synapse loss underlies the memory impairment evident in the early phase of AD and...

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Detalhes bibliográficos
Main Authors: Shankar, Ganesh M, Walsh, Dominic M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788538/
https://ncbi.nlm.nih.gov/pubmed/19930651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-48
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