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Structural model of ρ1 GABA(C) receptor based on evolutionary analysis: Testing of predicted protein–protein interactions involved in receptor assembly and function
The homopentameric ρ1 GABA(C) receptor is a ligand-gated ion channel with a binding pocket for γ-aminobutyric acid (GABA) at the interfaces of N-terminal extracellular domains. We combined evolutionary analysis, structural modeling, and experimental testing to study determinants of GABA(C) receptor...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788291/ https://ncbi.nlm.nih.gov/pubmed/19768800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.247 |
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