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Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse—Methamphetamine and 3,4-methylenedioxymethamphetamine

Methamphetamine (METH) is a major drug threat in the United States and worldwide. Monoclonal antibody (mAb) therapy for treating METH abuse is showing exciting promise and the understanding of how mAb structure relates to function will be essential for future development of these important therapies...

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Autors principals: Celikel, Reha, Peterson, Eric C, Owens, S Michael, Varughese, Kottayil I
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788288/
https://ncbi.nlm.nih.gov/pubmed/19760665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.244
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