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Domain 4 of the anthrax protective antigen maintains structure and binding to the host receptor CMG2 at low pH
Domain 4 of the anthrax protective antigen (PA) plays a key role in cellular receptor recognition as well as in pH-dependent pore formation. We present here the 1.95 Å crystal structure of domain 4, which adopts a fold that is identical to that observed in the full-length protein. We have also inves...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788282/ https://ncbi.nlm.nih.gov/pubmed/19722284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.238 |
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