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The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides

Methuselah (Mth) is a G protein-coupled receptor (GPCR) associated with longevity in Drosophila melanogaster. Previously, Stunted (Sun) was identified as a peptide agonist of Mth. Here, we identify two additional activators of Mth signaling: Drosophila Sex Peptide (SP) and a novel peptide (Serendipi...

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Hlavní autoři: Ja, William W, Carvalho, Gil B, Madrigal, Marisol, Roberts, Richard W, Benzer, Seymour
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788275/
https://ncbi.nlm.nih.gov/pubmed/19672878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.221
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