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Maternal and Zygotic aldh1a2 Activity Is Required for Pancreas Development in Zebrafish

We have isolated and characterized a novel zebrafish pancreas mutant. Mutant embryos lack expression of isl1 and sst in the endocrine pancreas, but retain isl1 expression in the CNS. Non-endocrine endodermal gene expression is less affected in the mutant, with varying degrees of residual expression...

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Autors principals: Alexa, Kristen, Choe, Seong-Kyu, Hirsch, Nicolas, Etheridge, Letitiah, Laver, Elizabeth, Sagerström, Charles G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788244/
https://ncbi.nlm.nih.gov/pubmed/20011517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008261
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