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Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis

Hox proteins form complexes with Pbx and Meis cofactors to control gene expression, but the role of Meis is unclear. We demonstrate that Hoxb1-regulated promoters are highly acetylated on histone H4 (AcH4) and occupied by Hoxb1, Pbx and Meis in zebrafish tissues where these promoters are active. Inh...

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Detalhes bibliográficos
Main Authors: Choe, Seong-Kyu, Lu, Peiyuan, Nakamura, Mako, Lee, Jinhyup, Sagerström, Charles G
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768649/
https://ncbi.nlm.nih.gov/pubmed/19853569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.08.007
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