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RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans

BACKGROUND: The strong familiality of living to extreme ages suggests that human longevity is genetically regulated. The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modif...

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Detalhes bibliográficos
Main Authors: Sebastiani, Paola, Montano, Monty, Puca, Annibale, Solovieff, Nadia, Kojima, Toshio, Wang, Meng C., Melista, Efthymia, Meltzer, Micah, Fischer, Sylvia E. J., Andersen, Stacy, Hartley, Stephen H., Sedgewick, Amanda, Arai, Yasumichi, Bergman, Aviv, Barzilai, Nir, Terry, Dellara F., Riva, Alberto, Anselmi, Chiara Viviani, Malovini, Alberto, Kitamoto, Aya, Sawabe, Motoji, Arai, Tomio, Gondo, Yasuyuki, Steinberg, Martin H., Hirose, Nobuyoshi, Atzmon, Gil, Ruvkun, Gary, Baldwin, Clinton T., Perls, Thomas T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788130/
https://ncbi.nlm.nih.gov/pubmed/20011587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008210
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