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Immune response in lung cancer mouse model mimics human anti-Hu reactivity

Most patients with paraneoplastic encephalomyelitis/sensory neuronopathy PEM/SN have small-cell lung cancer (SCLC) and develop antibodies against neuronal-specific Hu proteins, which are abnormally expressed in the tumor. Anti-Hu reactivity is present in ~16% of SCLC patients without PEM/SN. Here we...

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Detalhes bibliográficos
Main Authors: Kazarian, Meleeneh, Calbo, Joaquim, Proost, Natalie, Carpenter, Catherine L., Berns, Anton, Laird-Offringa, Ite A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788043/
https://ncbi.nlm.nih.gov/pubmed/19765830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.08.014
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