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The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway
After undergoing several rounds of divisions normal human fibroblasts enter a terminally non-dividing state referred to as cellular or replicative senescence. We cloned MORF4 (mortality factor on human chromosome 4), as a cellular senescence inducing gene that caused immortal cells assigned to compl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787921/ https://ncbi.nlm.nih.gov/pubmed/19769966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.09.015 |
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