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Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis
Ultra high molecular weight polyethylene is widely used as a bearing surface in prosthetic arthroplasty. Over time the generation of implant-derived wear particles can initiate an inflammatory reaction characterized by periprosthetic inflammation and ultimately bone resorption at the prosthetic bone...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787895/ https://ncbi.nlm.nih.gov/pubmed/19804908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.09.023 |
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