Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo

Previously we reported that plasma kallikrein and high molecular weight kininogen attach to the surface of dextran-coated superparamagnetic iron oxide nanoparticles (SPIONs) through the incompletely covered iron oxide core (Simberg et al., Biomaterials, 2009). Here we show that SPIONs also activate...

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Bibliographic Details
Main Authors: Simberg, Dmitri, Zhang, Wan-Ming, Merkulov, Sergei, McCrae, Keith, Park, Ji-Ho, Sailor, Michael J., Ruoslahti, Erkki
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787880/
https://ncbi.nlm.nih.gov/pubmed/19508879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.05.035
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