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ENERGETIC PERFORMANCE IS IMPROVED BY SPECIFIC ACTIVATION OF K(+) FLUXES THROUGH K(Ca) CHANNELS IN HEART MITOCHONDRIA

Mitochondrial volume regulation depends on K(+) movement across the inner membrane and a mitochondrial Ca(2+)-dependent K(+) channel (mitoK(Ca)) reportedly contributes to mitochondrial K(+) uniporter activity. Here we utilize a novel K(Ca) channel activator, NS11021, to examine the role of mitoK(Ca)...

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Detalles Bibliográficos
Main Authors: Aon, Miguel A., Cortassa, Sonia, Wei, An-Chi, Grunnet, Morten, O’Rourke, Brian
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787855/
https://ncbi.nlm.nih.gov/pubmed/19744465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.08.002
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