Acetylsalicylic acid (aspirin) reduces damage to reconstituted human tissues infected with Candida species by inhibiting extracellular fungal lipases

A reconstituted human tissue model was used to mimic Candida albicans and Candida parapsilosis infection in order to investigate the protective effects of acetylsalicylic acid (aspirin, ASA). We found that therapeutic concentrations of ASA reduced tissue damage in the in vitro infection model. We fu...

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Hauptverfasser: Trofa, David, Agovino, Mariangela, Stehr, Frank, Schäfer, Wilhelm, Rykunov, Dmitry, Fiser, András, Hamari, Zsuzsanna, Nosanchuk, Joshua D., Gácser, Attila
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787780/
https://ncbi.nlm.nih.gov/pubmed/19703582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2009.08.007
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