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Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence

Candida parapsilosis is a major cause of human disease, yet little is known about the pathogen’s virulence. We have developed an efficient gene deletion system for C. parapsilosis based on the repeated use of the dominant nourseothricin resistance marker (caSAT1) and its subsequent deletion by FLP-m...

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Bibliografiske detaljer
Main Authors: Gácser, Attila, Trofa, David, Schäfer, Wilhelm, Nosanchuk, Joshua D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974868/
https://ncbi.nlm.nih.gov/pubmed/17853941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32294
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