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Structural Determinants Underlying Constitutive Dimerization of Unoccupied Human Follitropin Receptors

The human follitropin receptor (hFSHR) is a G protein-coupled receptor (GPCR) central to reproductive physiology that is composed of an extracellular domain (ECD) fused to a serpentine region. Using bioluminescence resonance energy transfer (BRET) in living cells, we show that hFSHR dimers form cons...

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Detalhes bibliográficos
Main Authors: Guan, Rongbin, Wu, Xueqing, Feng, Xiuyan, Zhang, Meilin, Hébert, Terence E., Segaloff, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787667/
https://ncbi.nlm.nih.gov/pubmed/19800402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.09.023
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