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Convergent Synthesis of Stereodefined Exo-alkylidene-γ-Lactams from β-Halo Allylic Alcohols
[Image: see text] A convergent process for the assembly of stereodefined mono- and bicyclic exo-alkylidene γ-lactams is described that proceeds through the union of β-halo allylic alcohols, aromatic imines and CO. Overall, regio- and stereoselective Ti-mediated reductive cross-coupling, followed by...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787655/ https://ncbi.nlm.nih.gov/pubmed/19877599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol9022134 |
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