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The PAPS transporter PST-1 is required for heparan sulfation and is essential for viability and neural development in C. elegans

Sulfations of sugars, such as heparan sulfates (HS), or tyrosines require the universal sulfate donor 3′-phospho-adenosine-5′-phosphosulfate (PAPS) to be transported from the cytosol into the Golgi. Metazoan genomes encode two putative PAPS transporters (PAPST1 and PAPST2), which have been shown in...

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Main Authors: Bhattacharya, Raja, Townley, Robert A., Berry, Katherine L., Bülow, Hannes E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Company of Biologists 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787461/
https://ncbi.nlm.nih.gov/pubmed/19920077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.050732
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