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The PAPS transporter PST-1 is required for heparan sulfation and is essential for viability and neural development in C. elegans
Sulfations of sugars, such as heparan sulfates (HS), or tyrosines require the universal sulfate donor 3′-phospho-adenosine-5′-phosphosulfate (PAPS) to be transported from the cytosol into the Golgi. Metazoan genomes encode two putative PAPS transporters (PAPST1 and PAPST2), which have been shown in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787461/ https://ncbi.nlm.nih.gov/pubmed/19920077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.050732 |
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