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Presenilin-1 acts via Id1 to regulate the function of muscle satellite cells in a γ-secretase-independent manner

Muscle satellite cells are the resident stem cells of adult skeletal muscle. Here, we have examined the role of the multifunctional protein presenilin-1 (PS1) in satellite cell function. PS1 acts as a crucial component of the γ-secretase complex, which is required to cleave single-pass transmembrane...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ono, Yusuke, Gnocchi, Viola F., Zammit, Peter S., Nagatomi, Ryoichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787457/
https://ncbi.nlm.nih.gov/pubmed/19920078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.049742
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