An FcRn-dependent role for anti-flagellin in pathogenesis of immunoglobulin G-mediated colitis in mice

BACKGROUND & AIMS: The neonatal receptor for immunoglobulin (Ig)G (FcRn) protects monomeric IgG from catabolism in parenchymal and hematopoietic cells. In dendritic cells, FcRn also promotes presentation of antigens in association with IgG. Since IgGs with anti-bacterial specificity are a hallma...

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Bibliografiske detaljer
Main Authors: Kobayashi, Kanna, Qiao, Shuo-Wang, Yoshida, Masaru, Baker, Kristi, Lencer, Wayne I., Blumberg, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787451/
https://ncbi.nlm.nih.gov/pubmed/19664634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.07.059
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