Leukocyte Ig-like Receptor B4 (LILRB4) Is a Potent Inhibitor of FcγRI-mediated Monocyte Activation via Dephosphorylation of Multiple Kinases

The leukocyte immunoglobulin-like receptor (LILR) B4 belongs to a family of cell surface receptors that possesses cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the...

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Hlavní autoři: Lu, Hao Kim, Rentero, Carles, Raftery, Mark J., Borges, Luis, Bryant, Katherine, Tedla, Nicodemus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787346/
https://ncbi.nlm.nih.gov/pubmed/19833736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035683
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