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Calcium Bridge Triggers Capsid Disassembly in the Cell Entry Process of Simian Virus 40

The calcium bridge between the pentamers of polyoma viruses maintains capsid metastability. It has been shown that viral infection is profoundly inhibited by the substitution of lysine for glutamate in one calcium-binding residue of the SV40 capsid protein, VP1. However, it is unclear how the calciu...

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Detalhes bibliográficos
Main Authors: Kawano, Masa-aki, Xing, Li, Tsukamoto, Hiroko, Inoue, Takamasa, Handa, Hiroshi, Cheng, R. Holland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787333/
https://ncbi.nlm.nih.gov/pubmed/19822519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.015107
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