Roles of Disulfide Linkage and Calcium Ion-Mediated Interactions in Assembly and Disassembly of Virus-Like Particles Composed of Simian Virus 40 VP1 Capsid Protein

The simian virus 40 capsid is composed of 72 pentamers of VP1 protein. Although the capsid is known to dissociate to pentamers in vitro following simultaneous treatment with reducing and chelating agents, the functional roles of disulfide linkage and calcium ion-mediated interactions are not clear....

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Main Authors: Ishizu, Ken-Ichiro, Watanabe, Hajime, Han, Song-Iee, Kanesashi, Shin-Nosuke, Hoque, Mainul, Yajima, Hiroaki, Kataoka, Kohsuke, Handa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113898/
https://ncbi.nlm.nih.gov/pubmed/11119574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.61-72.2001
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