Targeted Knockdown of EGR-1 Inhibits IL-8 Production and IL-8-mediated Invasion of Prostate Cancer Cells through Suppressing EGR-1/NF-κB Synergy

IL-8 produced by prostate cancer cells may be responsible for the androgen-independent growth of advanced prostate cancers. Accumulating evidence from microarray analyses and animal genetic models highlights the central involvement of the transcription factor early growth response-1 (EGR-1) in prost...

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Hlavní autoři: Ma, Jiajia, Ren, Zijia, Ma, Yang, Xu, Lu, Zhao, Ying, Zheng, Chaogu, Fang, Yinghui, Xue, Ting, Sun, Baolin, Xiao, Weihua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787322/
https://ncbi.nlm.nih.gov/pubmed/19837667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016246
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