Activation of AMP-activated Protein Kinase Suppresses Oxidized Low-density Lipoprotein-induced Macrophage Proliferation

Macrophage-derived foam cells play important roles in the progression of atherosclerosis. We reported previously that ERK1/2-dependent granulocyte/macrophage colony-stimulating factor (GM-CSF) expression, leading to p38 MAPK/ Akt signaling, is important for oxidized low density lipoprotein (Ox-LDL)-...

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Detalhes bibliográficos
Main Authors: Ishii, Norio, Matsumura, Takeshi, Kinoshita, Hiroyuki, Motoshima, Hiroyuki, Kojima, Kanou, Tsutsumi, Atsuyuki, Kawasaki, Shuji, Yano, Miyuki, Senokuchi, Takafumi, Asano, Tomoichiro, Nishikawa, Takeshi, Araki, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787318/
https://ncbi.nlm.nih.gov/pubmed/19843515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028043
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