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Non-proteolytic Regulation of p53-mediated Transcription through Destabilization of the Activator·Promoter Complex by the Proteasomal ATPases
It has been shown previously that sub-complexes of the 26 S proteasome can regulate gene expression via non-proteolytic mechanisms. One such mechanism is the disruption of activator·promoter complexes in an ATP-dependent fashion, which was discovered in the context of the yeast Gal4 system. This act...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787313/ https://ncbi.nlm.nih.gov/pubmed/19846554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017277 |
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