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Non-proteolytic Regulation of p53-mediated Transcription through Destabilization of the Activator·Promoter Complex by the Proteasomal ATPases

It has been shown previously that sub-complexes of the 26 S proteasome can regulate gene expression via non-proteolytic mechanisms. One such mechanism is the disruption of activator·promoter complexes in an ATP-dependent fashion, which was discovered in the context of the yeast Gal4 system. This act...

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Detalhes bibliográficos
Main Authors: Kim, Young-Chan, Wu, Shwu-Yuan, Lim, Hyun-Suk, Chiang, Cheng-Ming, Kodadek, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787313/
https://ncbi.nlm.nih.gov/pubmed/19846554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017277
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