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Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein

Caenorhabditis elegans fem-3 binding factor (FBF) is a founding member of the PUMILIO/FBF (PUF) family of mRNA regulatory proteins. It regulates multiple mRNAs critical for stem cell maintenance and germline development. Here, we report crystal structures of FBF in complex with 6 different 9-nt RNA...

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Détails bibliographiques
Auteurs principaux: Wang, Yeming, Opperman, Laura, Wickens, Marvin, Hall, Traci M. Tanaka
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787170/
https://ncbi.nlm.nih.gov/pubmed/19901328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812076106
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