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In Situ IL-12/23p40 Production during Mycobacterial Infection Is Sustained by CD11b(high) Dendritic Cells Localized in Tissue Sites Distinct from Those Harboring Bacilli

Although IL-12/23p40 is known to play a major role in host resistance to Mycobacterium spp, the cellular source, tissue localization, and regulation of p40 production during mycobacterial infection in vivo has been unclear. In this study, we used IL-12/23p40eYFP (yet40) reporter mice to track expres...

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Dettagli Bibliografici
Autori principali: Rothfuchs, Antonio Gigliotti, Egen, Jackson G., Feng, Carl G., Antonelli, Lis R. V., Bafica, Andre, Winter, Nathalie, Locksley, Richard M., Sher, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786988/
https://ncbi.nlm.nih.gov/pubmed/19454688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900074
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