Interleukin-15 Enhances Proteasomal Degradation of Bid in Normal Lymphocytes: Implications for Large Granular Lymphocyte Leukemias

Large granular lymphocyte (LGL) leukemia is a clonal proliferative disease of T and natural killer (NK) cells. Interleukin (IL)-15 is important for the development and progression of LGL leukemia and is a survival factor for normal NK and T memory cells. IL-15 alters expression of Bcl-2 family membe...

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Main Authors: Hodge, Deborah L., Yang, Jun, Buschman, Matthew D., Schaughency, Paul M., Dang, Hong, Bere, William, Yang, Yili, Savan, Ram, Subleski, Jeff J., Yin, Xiao-Ming, Loughran, Thomas P., Young, Howard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786937/
https://ncbi.nlm.nih.gov/pubmed/19366803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3735
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