MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice

Oxidative myofibers, also known as slow-twitch myofibers, help maintain the metabolic health of mammals, and it has been proposed that decreased numbers correlate with increased risk of obesity. The transcriptional coactivator PPARγ coactivator 1α (PGC-1α) plays a central role in maintaining levels...

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Detalhes bibliográficos
Main Authors: Roth, Rachel J., Le, Annie M., Zhang, Lei, Kahn, Mario, Samuel, Varman T., Shulman, Gerald I., Bennett, Anton M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786792/
https://ncbi.nlm.nih.gov/pubmed/19920356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39054
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