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A Default Pathway of Memory CD8 T Cell Differentiation after Dendritic Cell Immunization Is Deflected by Encounter With Inflammatory Cytokines During Antigen-Driven Proliferation

Inflammatory cytokines induced by infection or vaccination with adjuvant act directly or indirectly on CD8 T-cells to modulate their expansion, contraction and acquisition of memory characteristics. Importantly, the initial exposure of naïve T-cells to inflammatory cytokines may occur prior to, duri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pham, Nhat-Long L., Badovinac, Vladimir P., Harty, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786780/
https://ncbi.nlm.nih.gov/pubmed/19635915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901203
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